Out Of Tone

Nervous System & Special Senses

{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"The \u0027floppy infant\u0027 is a clinical conundrum well described in pediatric textbooks; this refers to a child with generalized hypotonia, as manifested by a frog-like posture of the lower limbs when supine, and head lag.\n\nWhile relatively easy to recognize, this presentation is often a significant diagnostic challenge, given the vast array of differentials; a structured approach is essential to localize the problem to a specific region of the nervous system, and thus narrow down the likely etiologies.\n \nTo do this, one must first appreciate that the causes of infantile hypotonia can be broadly divided into those which are central (i.e. the upper motor neuron), and peripheral (involving the lower motor neuron and motor unit).\n\nDifferentiating be"}]}

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