Continuous

Gastrointestinal System


Step 1: View Clinicals

{"ops":[{"insert":"A 54-year-old man presents with watery diarrhea for two months. The diarrhea is mainly nocturnal and unrelated to food intake. It does not abate with fasting. The stools are odorless, and without blood or mucus. There is no history of significant weight loss.\n\nOver the last month, he has sought medical attention from several primary care practitioners. He was, separately, prescribed a course of loperamide and a course of metronidazole, both of which were without effect. He is currently not on any medications.\n\nHis medical, surgical, and family histories are unremarkable. He denies any history of allergies, recent travel to tropical areas, food intoxication, laxative abuse, or use of over-the-counter drugs or herbal medications.\n\nHe is found to be mildly dehydrated, but with stable vital parameters. A complete blood count, renal functions, and liver profile are all normal. However, an electrolyte assay is significant for hypokalemia (2.6 mEq\/L) and hypocalcemia (3.2 mmol\/L), while an arterial blood gas assay shows non-anion gap metabolic acidosis (pH: 7.15, bicarbonate level: 6.4 mmol\/L).\n \nHe is stabilized and resuscitated appropriately. Follow-up investigations show a serum TSH of 1.5 mIU\/L (normal: 0.4-4); no leukocytes, bacteria, viruses, fungi, or parasites on stool analysis; and a fecal osmotic gap of 15 mmol\/L (normal: 50-100).\n"},{"insert":"\n"},{"insert":{"image":"\/storage\/case-images\/pd\/PD-M-251_en.png"}},{"insert":"\n"}]}

Step 2: Order Relevant Investigations

1. Colonoscopy
2. Neuroendocrine Tumor Screen

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