Up Above

Immune System

{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"Oral ulcers are extremely common, affecting almost every individual at some point in their life. The range of underlying causes is similarly broad.\n\nHowever, in this patient, the temporal relationship between the orogenital sex and appearance of the ulcer is strongly suggestive of a sexually transmitted infection (STI).\n\nIn this respect, the two most important STIs to consider are herpes simplex (HSV) and syphilis. Note that HSV typically causes painful ulcers - but those of syphilis are characteristically painless.\n\nIt should be kept in mind that painless oral ulcers may also be caused by malignancies, autoimmune diseases (especially SLE) and erythema multiforme\/Stevens-Johnson syndrome. However, these etiologies are best considered only i"}]}

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