Multisystem Processes & Disorders

{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"This patient has experienced a generalized convulsion and is now drowsy and confused. He is also febrile.\n\nThe differential diagnosis of fever and generalized convulsions is broad and includes central nervous system (CNS) infections, cerebral hemorrhage, endocrinopathies and toxic causes, among others.\n\nHowever, note that his core temperature is over 40 Celsius - i.e. severe hyperthermia. This narrows down the differential diagnosis considerably, to CNS infections, heat stroke, neuroleptic malignant syndrome or malignant hyperthermia.\n\nThe absence of meningism or focal neurological signs makes CNS infections or hemorrhage unlikely. The normal CT brain and lumbar puncture definitively excludes these diagnoses.\n\nThe neuroleptic malignant synd"}]}

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