Immune System

{"ops":[{"insert":"Diagnosis and reasoning"},{"insert":"\n","attributes":{"header":1}},{"insert":"This returning traveler has presented with a high fever, headache, and photophobia. Examination shows neck stiffness, positive Kernig and Brudzinski signs, and a positive jolt accentuation test. This should be considered to be a central nervous system (CNS) infection until proven otherwise.\n \nA lumbar puncture is an essential next step. Blood cultures should be obtained in parallel, while empirical antibiotic therapy should be commenced as soon as samples have been obtained.\n \nNote also that preceding computed tomography (CT) of the brain is unnecessary, as he does not meet any of the criteria which would mandate this (i.e. age over 60 years, immunosuppression, presence of a known CNS lesion, features of raised intracranial pressure, altere"}]}

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