An 11 month old male infant of Laotian origin presents with reduced activity and a lack of interest in his surroundings for two months. His stools are not bloody or melenic, but his mother says that his abdomen feels swollen. She also complains that the infant cannot stand yet, despite having started to crawl three months ago. All other developmental milestones are age appropriate. He consumes a diet of rice, vegetables and meat in addition to being breastfed thrice a day after meals. Feeding has become difficult of late. All vaccinations are up to date.
Hb: 5.4 g/dl (10.5-13.5) RBC: 6.1*10^9/ml (3.7-5.3*10^9) MCV: 58 fl (70-86) MCHC: 27g/dl (32-36) RDW-CV: 11.5% (11.5-16) WBC, Platelets: within normal parameters
There are hypochromic microcytic red blood cells and target cells with occasional tear drop cells. All other cell lines appear normal.
Serum Iron: 24 micromol/L (11-27) Serum Ferritin: 167 micrograms/L (30-500) Total Iron Binding Capacity: 51 micromol/L (45-66) Transferrin saturation: 47.05% (15-55)
HbE: 56% HbF: 41% HbA2: 3%