A 33 year old woman presents with progressive hair growth on her face and chest for 6 months, and irregular periods occurring every 2 to 3 months, for 5 months. Prior to this, her menstrual periods occurred at regular 30 day cycles. Her medical history is unremarkable and she is not on any medications.
TSH, Estrogen, Prolactin, Progesterone, DHEAS, 17-OH Progesterone: normal Testosterone: 392 ng/dL (high) 48h low dose dexamethasone suppression test: cortisol & DHEAS suppressed; testosterone elevated
An abdominal and transvaginal ultrasound scan are performed. No abnormalities are detected.
The CT scan of the abdomen and pelvis shows no abnormalities.
There are elevated testosterone concentrations in the right ovarian vein.