Immune System

{"ops":[{"insert":"Diagnosis of infective endocarditis"},{"insert":"\n","attributes":{"header":1}},{"insert":"The variability in the clinical presentation of IE and the importance of an early, accurate diagnosis have led to the proposition of the Duke Criteria, which stratify patients with suspected IE into three categories (definite, possible, and rejected cases), based on major (pathological) and minor (clinical) criteria, as follows: \r\n \r\nMajor criteria: Blood culture positive for IE; typical microorganisms consistent with IE from 2 separate blood cultures; single positive blood culture for Coxiella burnetii or anti-phase 1 IgG antibody titer \u22651:800; evidence of endocardial involvement; echocardiogram positive for IE\r\n\r\nMinor criteria: Predisposition, predisposing heart condition, or history of intravenous drug use; fever, temperature \u003E38\u00b0C; "}]}

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