Hormone replacement therapy

Replacement

Overview

A series of individuals with problems arising from menopause. Can you correctly treat them all?


  1. Breast cancer screening in women on HRT
  2. HRT and mitigation of cardiovascular disease risk
  3. HRT in women who are post-hysterectomy
  4. HRT risks and benefits
  5. HRT usage in hot flashes
  6. Management of cardiovascular disease in postmenopausal women
  7. Natural vs. synthetic progestogens and breast cancer
  8. Postmenopausal symptoms
  1. BERAL V, BULL D, REEVES G, MILLION WOMEN STUDY COLLABORATORS. Endometrial cancer and hormone-replacement therapy in the Million Women Study. Lancet [online] 2005 Apr 30-May 6, 365(9470):1543-51 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/15866308
  2. BRINTON LA, FELIX AS. Menopausal hormone therapy and risk of endometrial cancer. J Steroid Biochem Mol Biol [online] 2014 Jul:83-9 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/23680641
  3. DALAL PK, AGARWAL M. Postmenopausal syndrome Indian J Psychiatry [online] 2015 Jul, 57(Suppl 2):S222-S232 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539866
  4. GRADY D, GEBRETSADIK T, KERLIKOWSKE K, ERNSTER V, PETITTI D. Hormone replacement therapy and endometrial cancer risk: a meta-analysis. Obstet Gynecol [online] 1995 Feb, 85(2):304-13 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/7824251
  5. HANEY AF, WILD RA. Options for hormone therapy in women who have had a hysterectomy. Menopause [online] 2007 May-Jun, 14(3 Pt 2):592-7; quiz 598-9 [viewed 18 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/17476150
  6. HERRINTON LJ, WEISS NS. Postmenopausal unopposed estrogens. Characteristics of use in relation to the risk of endometrial carcinoma. Ann Epidemiol [online] 1993 May, 3(3):308-18 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/8275205 CAMPAGNOLI C, CLAVEL-CHAPELON F, KAAKS R, PERIS C, BERRINO F. Progestins and progesterone in hormone replacement therapy and the risk of breast cancer. J Steroid Biochem Mol Biol [online] 2005 Jul, 96(2):95-108 [viewed 18 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/15908197]
  7. HOU N, HONG S, WANG W, OLOPADE OI, DIGNAM JJ, HUO D. Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density. J Natl Cancer Inst [online] 2013 Sep 18, 105(18):1365-72 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/24003037
  8. Hormone replacement therapy and endometrial cancer risk: A meta-analysis. International Journal of Gynecology & Obstetrics [online] 1995 October [viewed 16 July 2016] Available from: doi:10.1016/0020-7292(95)80037-D
  9. JOFFE H, SOARES CN, COHEN LS. Assessment and treatment of hot flushes and menopausal mood disturbance. Psychiatr Clin North Am [online] 2003 Sep, 26(3):563-80 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/14563098
  10. LAWLOR DA, SMITH GD. Cardiovascular risk and hormone replacement therapy. Curr Opin Obstet Gynecol [online] 2006 Dec, 18(6):658-65 [viewed 18 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/17099339
  11. OEFFINGER KC, FONTHAM ET, ETZIONI R, HERZIG A, MICHAELSON JS, SHIH YC, WALTER LC, CHURCH TR, FLOWERS CR, LAMONTE SJ, WOLF AM, DESANTIS C, LORTET-TIEULENT J, ANDREWS K, MANASSARAM-BAPTISTE D, SASLOW D, SMITH RA, BRAWLEY OW, WENDER R, AMERICAN CANCER SOCIETY. Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society. JAMA [online] 2015 Oct 20, 314(15):1599-614 [viewed 18 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/26501536
  12. PACI E, EUROSCREEN WORKING GROUP. Summary of the evidence of breast cancer service screening outcomes in Europe and first estimate of the benefit and harm balance sheet. J Med Screen [online] 2012:5-13 [viewed 18 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/22972806
  13. Reorganized text. JAMA Otolaryngol Head Neck Surg [online] 2015 May 1, 141(5):428 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/25996397
  14. SASSARINI J, LUMSDEN MA. Hot flushes: are there effective alternatives to estrogen? Menopause Int [online] 2010 Jun, 16(2):81-8 [viewed 22 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/20729500
  15. STEINER AZ, XIANG M, MACK WJ, SHOUPE D, FELIX JC, LOBO RA, HODIS HN. Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. Obstet Gynecol [online] 2007 Mar, 109(3):581-7 [viewed 16 July 2016] Available from: http://www.ncbi.nlm.nih.gov/pubmed/17329508