Acidosis

Balance

Overview

Three patients with metabolic acidosis. Three different underlying causes. Can you manage all of them successfully?


  1. Alkalinization in salicylate poisoning
  2. Cerebral edema in diabetic ketoacidosis
  3. Early alkalinization in salicylate poisoning
  4. Fluid management in diabetic ketoacidosis
  5. Gastric Decontamination in salicylate poisoning
  6. Hemodialysis vs. Continuous Renal Replacement Therapy (CRRT)
  7. Indications for hemodialysis in salicylate poisoning
  8. Metformin Induced Lactic Acidosis (MALA)
  9. Monitoring plasma salicylate levels
  10. Precipitating factors of diabetic ketoacidosis
  11. Selection of fluid for alkalinisation
  12. Usage of activated charcoal
  13. Use of insulin in diabetic ketoacidosis
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  4. GLEN E HASTINs. Aspirin overdose. [online] 2005 November 10. Available from: http://wichita.kumc.edu/hastings/aspirin_overdose.pdf
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  6. O'MALLEY GERALD F.. Emergency Department Management of the Salicylate-Poisoned Patient. Emergency Medicine Clinics of North America [online] 2007 May, 25(2):333-346 [viewed 22 July 2014] Available from: doi:10.1016/j.emc.2007.02.012
  7. RENDA F, MURA P, FINCO G, FERRAZIN F, PANI L, LANDONI G. Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review. Eur Rev Med Pharmacol Sci [online] 2013 Feb:45-9 [viewed 24 July 2014] Available from: http://www.ncbi.nlm.nih.gov/pubmed/23436666
  8. Ravindra L. Mehta . Supportive Therapies:Intermittent Hemodialysis,Continuous Renal Replacement Therapies, and Peritoneal Dialysis. [viewed 22 July 2014] Available from: http://www.cybernephrology.ualberta.ca/cn/Schrier/Volume1/chap19/ADK1_19_1-3.pdf
  9. TRACHTENBARG DE. Diabetic ketoacidosis. Am Fam Physician [online] 2005 May 1, 71(9):1705-14 [viewed 22 July 2014] Available from: http://www.ncbi.nlm.nih.gov/pubmed/15887449
  10. VON MACH MA, SAUER O, SACHA WEILEMANN L. Experiences of a poison center with metformin-associated lactic acidosis. Exp Clin Endocrinol Diabetes [online] 2004 Apr, 112(4):187-90 [viewed 24 July 2014] Available from: doi:10.1055/s-2004-817931